Gio

26

Feb

2009

Condensazione Aldolica
CHIMICA ORGANICA
Scritto da Coviello   
The Claisen-Schmidt reaction involves the synthesis of an a,b-unsaturated ketone by the condensation of an aromatic aldehyde with a ketone.  The aromatic aldehyde possesses no hydrogens a-to the carbonyl group, it cannot therefore undergo self condensation but reacts rapidly with the ketone present.The initial aldol adduct cannot be isolated as it dehydrates readily under the  reaction conditions to give an a,b-unsaturated ketone.  This unsaturated ketone also possesses activated hydrogens a-to a carbonyl group and may condense with another molecule of the aldehyde.

In this experiment you will carry out the base catalysed aldol condensation of p-tolualdehyde with acetone.  The product will be purified by recrystallisation and its structure determined using the spectra provided.

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